The effect of betaine on broilers infected experimentally with Clostridium perfringens

Document Type : Research article

Authors

1 Animal Health Research Institute -Agriculture Research Center

2 Poultry Diseases Department, Faculty of Veterinary Medicine, Assiut University

Abstract

ABSTRACT
This study was investigated the effect of betaine on blood biochemical parameters, histopathological picture and intestinal integrity in broiler chickens challenged with C.perfringens . A total of 120, one- day-old broiler chicks (Rose chickens) were randomly assigned to one of three treatments: 1) negative control (NC), 2) infected group (IG) and 3) treated group (TG), which were dosed with 1.0 ml betaine/L drinking water, from day one until the conclusion of the end of experiment. At 14 days of age, both the infected and treated groups were orally inoculated with 1×104 sporulated oocysts of mixed Eimeria species. Five days later, the same groups were orally challenged with a toxigenic strain of C. perfringens by inoculating each bird with 2 ml of broth culture (1×108 CFU) per bird. Betaine decreased the severity of necrotic enteritis in (TG) by decreasing the severity of brown diarrhea resulting in a significant (P< 0.05) reduction in the total count of C. perfringens (CFU/g) in the cecum in comparison to the infected and control groups. Betaine supplementation improves blood parameters. Additionally, betaine treatment diminishes pathological lesions in comparison to the infected group.

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